Pengaruh antara Penggunaan Teknologi Informasi, Implementasi Strategi Diferensiasi, dan Kualitas Layanan dalam Mencapai Keunggulan Bersaing pada Rumah Sakit Haji Makassar

Perkembangan persaingan antar Perusahaan semakin ketat baik pada tingkat regional maupun global. Pada sebagian besar industri jasa, kualitas layanan secara umum diterima sebagai suatu faktor penentu (key factor). Zeithaml dan Berry menyatakan bahwa kualitas layanan merupakan strategi yang mendasar dalam upaya Perusahaan meraih sukses dan keberlanjutan dalam lingkungan bisnis yang ketat. Kualitas pelayanan dapat dipengaruhi oleh faktor-faktor seperti penggunaan teknologi informasi dan implementasi strategi diferensiasi. Tujuan penelitian ini adalah untuk menganalisis pengaruh penggunaan teknologi informasi terhadap kualitas pelayanan, pengaruh kualitas pelayanan terhadap keunggulan bersaing, dan pengaruh implementasi strategi diferensiasi terhadap keunggulan bersaing. Penelitian ini merupakan penelitian explanatory adalah untuk menjelaskan hubungan kausal antara variabel melalui proposisi konfirmatory dan pengujian. Dalam penelitian ini teknik analisis yang digunakan Structural Equation Modelling (SEM). Perwakilan jumlah sampel yang digunakan dalam penelitian yang sesuai dengan menggunakan teknik analisis SEM.Teknologi informasi memiliki pengaruh positif dan signifikan terhadap kualitas pelayanan, strategi diferensiasi memiliki pengaruh positif dan signifikan terhadap keunggulan kompetitif, kualitas layanan memiliki pengaruh positif dan signifikan terhadap keunggulan kompetitif. Teknologi informasi dan strategi diferensiasi dapat memengaruhi kualitas pelayanan dan kualitas pelayanan itu sendiri akan memengaruhi keunggulan bersaing rumah sakit. Kesimpulannya adalah penggunaan teknologi informasi berpengaruh positif dan signifikan terhadap kualitas pelayanan sedangkan strategi diferensiasi dan kualitas layanan berpengaruh positif dan signifikan terhadap keunggulan bersaing

Positioning Analysis of Islamic Bank Vis-àvis Conventional Bank in Indonesia Using Parametric Sfa and Dfa Methods15

This study will measure and compare the efficiency of Conventional and Islamic banks in Indonesia using parametric approach stochastic frontier approach (SFA) and distribution free approach (DFA). These measurements will provide comprehensive and robust results of efficiency of individual bank compare to its peer group. The results using parametric SFA show that in 2002, conventional banks (0.79) were slightly more efficient than Islamic banks (0.77), while in 2003, the efficiency of Islamic banks improved to 0.84 and the efficiency of conventional banks worsen to 0.76, so that Islamic banks have become more efficient than conventional banks. Conventional and Islamic banks have been improving and converged to the highest level of efficiency (1.00) since 2004. The DFA results show that conventional banks (0.89) are only slightly more efficient than Islamic banks (0.87). Conventional public bank (0.93) is the most efficient, while Islamic regional bank (0.84) is the least efficient. Moreover, efficient banks (conventional and Islamic) do not always have lower OCOI (operating costs divided by operating income), while banks with better OCOI usually are more profitable (have better return on assets or ROA). Therefore, technically, Islamic banks have shown their readiness to compete head to head with their conventional counterparts. However, other aspects, such as, number of networks and branches, service quality, convenience, products and services provided, human resources, and pricing, should have become the next priorities for improvements.JEL Classification : C10, C33, G21, G2

Optimized Planar Penning Traps for Quantum Information Studies

A one-electron qubit would offer a new option for quantum information science, including the possibility of extremely long coherence times. One-quantum cyclotron transitions and spin flips have been observed for a single electron in a cylindrical Penning trap. However, an electron suspended in a planar Penning trap is a more promising building block for the array of coupled qubits needed for quantum information studies. The optimized design configurations identified here promise to make it possible to realize the elusive goal of one trapped electron in a planar Penning trap for the first time - a substantial step toward a one-electron qubit

Identifikasi Mutasi Heteroplasmi A3243g Dna Mitokondria Dan Studi Pewarisan Maternal Pada Pasien Diabetes Melitus Tipe 2

Mutasi A3243G DNA mitokondria (mtDNA) adalah mutasi subsitusi basa A ke G pada posisi 3243 gen tRNALeu. Salah satu fenotipe klinis yang disebabkan mutasi A3243G mtDNA adalah MIDD (Maternally Inherited Diabetes and Deafness) yang merupakan salah satu bentuk diabetes melitus (DM) tipe 2. Penelitian ini bertujuan untuk mengidentifikasi mutasi heteroplasmi A3243G manusia Indonesia pada pasien DM tipe 2 dan mempelajari pewarisan maternal mutasi A3243G hingga tiga generasi dengan memanfaatkan metode PCRRFLP(Polymerase Chain Reaction–Restriction Fragments Length Polymorphism), PASA (PCR-Amplification of Specific Allelle) dan PCR-SSCP (PCR-Single Strand Conformation Polymorphism). mtDNA diperoleh dari hasil lisis sampel darah. Hasil penelitian menunjukkan bahwa mutasi A3243G teridentifikasi pada 2 dari 101 pasien DM tipe 2. Mutasi heteroplasmi A3243G dapat ditunjukkan dari hasil PCR-RFLP dan PASA. Hasil RFLP menunjukkan adanya tiga fragmen, masing-masing yaitu fragmen utuh 294, 182 dan 112 pb sebagai hasil restriksi enzim ApaI. Hasil PASA menunjukkan adanya dua fragmen dengan ukuran 200 pb pada alel normal dan mutan. Mutasi A3243G yang teridentifikasi mempunyai tingkat heteroplasmi yang rendah karena tidak dapat teridentifikasi dengan direct sequencing dan PCR-SSCP (akrilamid:bis-akrilamid 49:1%). Pewarisan maternal mutasi heteroplasmi A3243G dapat teridentifikasi dengan PASA

An objective global climatology of polar lows based on reanalysis data

Here an objective global climatology of polar lows has been developed. In order to obtain objective detection criteria the efficacy of several parameters for separating polar lows from other cyclones has been investigated. This parameter efficacy has been compared for polar lows subjectively identified by experts and for all kind of extra-tropical cyclones. The comparison is based on the ERA-Interim reanalysis from 1979 - 2016 and the higher resolution Arctic System Reanalysis from 2000 - 2012. The parameters found to be the most effective at separating polar lows from all other kinds of synoptic and meso-scale cyclones were the difference between the mean sea-level pressure of the low and its surroundings, the difference in the potential temperature between the sea surface and the 500 hPa level, and the tropopause wind poleward of the system. Other parameters often used for distinguishing, such as the 10m wind speed and the temperature difference between the sea surface and the 700 hPa level were found to be less effective. Investigation of the climatologies reveals that PLs occur in all maritime basins at high latitudes, but with high density in the vicinity of the sea-ice edge and coastal zones. The regions showing the highest degree of polar-low activity are the Denmark Strait and the Nordic Seas. Especially the most intense polar lows occur in these two regions. In the North Atlantic and Pacific the main polar-low season ranges from November to March. In the Southern Hemisphere polar lows are mainly detected between 50 - 65'S from April to October, indicating that this hemisphere compared to its northern counterpart has a two months longer, but less intense, polar-low season. No significant hemispheric long-term trends are observed, although some regions, such as the Denmark Strait and the Nordic Sea experience significant downward and upward trends in polar lows, respectively, over the last decades. For intense polar lows a significant decaying trend has been observed for the northern hemisphere

IDENTIFIKASI MUTASI HETEROPLASMI A3243G DNA MITOKONDRIA DAN STUDI PEWARISAN MATERNAL PADA PASIEN DIABETES MELITUS TIPE 2

Mutasi A3243G DNA mitokondria (mtDNA) adalah mutasi subsitusi basa A ke G pada posisi 3243 gen tRNALeu. Salah satu fenotipe klinis yang disebabkan mutasi A3243G mtDNA adalah MIDD (Maternally Inherited Diabetes and Deafness) yang merupakan salah satu bentuk diabetes melitus (DM) tipe 2. Penelitian ini bertujuan untuk mengidentifikasi mutasi heteroplasmi A3243G manusia Indonesia pada pasien DM tipe 2 dan mempelajari pewarisan maternal mutasi A3243G hingga tiga generasi dengan memanfaatkan metode PCRRFLP(Polymerase Chain Reaction–Restriction Fragments Length Polymorphism), PASA (PCR-Amplification of Specific Allelle) dan PCR-SSCP (PCR-Single Strand Conformation Polymorphism). mtDNA diperoleh dari hasil lisis sampel darah. Hasil penelitian menunjukkan bahwa mutasi A3243G teridentifikasi pada 2 dari 101 pasien DM tipe 2. Mutasi heteroplasmi A3243G dapat ditunjukkan dari hasil PCR-RFLP dan PASA. Hasil RFLP menunjukkan adanya tiga fragmen, masing-masing yaitu fragmen utuh 294, 182 dan 112 pb sebagai hasil restriksi enzim ApaI. Hasil PASA menunjukkan adanya dua fragmen dengan ukuran 200 pb pada alel normal dan mutan. Mutasi A3243G yang teridentifikasi mempunyai tingkat heteroplasmi yang rendah karena tidak dapat teridentifikasi dengan direct sequencing dan PCR-SSCP (akrilamid:bis-akrilamid 49:1%). Pewarisan maternal mutasi heteroplasmi A3243G dapat teridentifikasi dengan PASA.Kata kunci : Mutasi A3243G, mutasi heteroplasmi, PCR-RFLP, PASA, PCR-SSCP, MIDD, direct sequencing

Characterisation of the Stromal Microenvironment in Lobular Breast Cancer

SIMPLE SUMMARY: Invasive lobular breast cancer (ILC) accounts for approximately 5–15% of breast cancers, and although response rates to treatments are initially good, an ILC diagnosis is associated with adverse long-term outcomes; better treatments, specifically targeted to this sub-type of breast cancer, are required to improve patient survival. The tumor microenvironment (TME) plays an important role in determining how cancers respond to treatment, and in this study, we carried out an in-depth analysis of the TME in ILC following laser-capture microdissection of the tumor stroma, and analysis of primary cancer-associated fibroblasts (CAFs), which comprise the majority of non-malignant cells within tumors. This identified changes in genes involved in regulation of the extracellular matrix and also growth factor signaling pathways that were differentially regulated in ILC. Further analysis of breast cancer datasets showed that two of these genes which encode a secreted metalloproteinase (PAPPA) and a metalloproteinase inhibitor (TIMP2) were associated with survival outcomes in ILC. ABSTRACT: Invasive lobular carcinoma (ILC) is the second most common histological subtype of breast cancer, and it exhibits a number of clinico-pathological characteristics distinct from the more common invasive ductal carcinoma (IDC). We set out to identify alterations in the tumor microenvironment (TME) of ILC. We used laser-capture microdissection to separate tumor epithelium from stroma in 23 ER+ ILC primary tumors. Gene expression analysis identified 45 genes involved in regulation of the extracellular matrix (ECM) that were enriched in the non-immune stroma of ILC, but not in non-immune stroma from ER+ IDC or normal breast. Of these, 10 were expressed in cancer-associated fibroblasts (CAFs) and were increased in ILC compared to IDC in bulk gene expression datasets, with PAPPA and TIMP2 being associated with better survival in ILC but not IDC. PAPPA, a gene involved in IGF-1 signaling, was the most enriched in the stroma compared to the tumor epithelial compartment in ILC. Analysis of PAPPA- and IGF1-associated genes identified a paracrine signaling pathway, and active PAPP-A was shown to be secreted from primary CAFs. This is the first study to demonstrate molecular differences in the TME between ILC and IDC identifying differences in matrix organization and growth factor signaling pathways

Single electron emission in two-phase xenon with application to the detection of coherent neutrino-nucleus scattering

We present an experimental study of single electron emission in ZEPLIN-III, a two-phase xenon experiment built to search for dark matter WIMPs, and discuss applications enabled by the excellent signal-to-noise ratio achieved in detecting this signature. Firstly, we demonstrate a practical method for precise measurement of the free electron lifetime in liquid xenon during normal operation of these detectors. Then, using a realistic detector response model and backgrounds, we assess the feasibility of deploying such an instrument for measuring coherent neutrino-nucleus elastic scattering using the ionisation channel in the few-electron regime. We conclude that it should be possible to measure this elusive neutrino signature above an ionisation threshold of $\sim$3 electrons both at a stopped pion source and at a nuclear reactor. Detectable signal rates are larger in the reactor case, but the triggered measurement and harder recoil energy spectrum afforded by the accelerator source enable lower overall background and fiducialisation of the active volume

Corporate political activity in less developed countries:The Volta River Project in Ghana, 1958-66

The article expands existing categorisations of political and economic governance by including literature on less developed countries (LDCs). In four consecutive negotiations between the US multinational Kaisers and the US and Ghana governments in the early 1960s, it is argued that the company reached levels of influence that are at odds with existing explanations. In order to understand corporate political activities in LDCs, analysis needs to go beyond static factors (political risk) and include dynamic factors such as diplomatic relations and 'arenas of power', and consider the role of the investor's home country relative to the host economy

Spring 1959

Seed testing - A Service for You by Miss Jessie L. Anderson (page 1) Increased Interest in Two-Year Turf Course by Fred P. Jeffrey - Director of Stockbridge (4) From the Editor (4) Message From Winter School President of 1959 (5) Turf club News (6) Number One Graduate (8) Liquid Fertilization by A.B. Longo (9) Public School Grounds by James Woodhouse (12) Comments on the 1959 Winter School (14) Picture - Stockbridge Turf Majors (16) Picture - Honorary Members of Turf Management Club (17) Letter on Chemical Compatibility (18) The Most Outstanding Turf Senior for 1958 (19) What it Means to be a Turf Manager by R. Russell (20) 10 Steps to a Better Lawn by P. Pedrazzi (24) A Scene to Remember (25) I switched from Hots to Cools by J. Spodnik (26) Why Attend Turfgrass Conferences (27) Picture - Winter School for Turf Managers - 1959 (29) Picture - University of Masssachusetts Annual Turfgrass Conference (30) Organic Fertilizers by O.J. Noer (A-1) Inorganic Fertilizers by Charles Winchell (A-1) Urea Formaldehyde by G.F. Stewart (A-2) Phosphorus and Potash Fertilization by Raph Donaldson (A-3) Questions on Fertilization to the Panel (A-4) Cemetery Maintenance by S.E. Robbins (A-6) Lime by Anson Brewer (A-6) Limited Budgets by R.W. Sharkey (A-7) Fertilization of Park Turf by E.J. Pyle (A-7) Disease and Insect Control by Orlando Capizzi (A-8) Cost of Establishing Turf by Victor Taricano (A-9) Question and Answers (A-10) Control of Pests of Ornamentals and Turf Occuring on Golf Courses by John C. Schread (A-12) Behind the Scenes in Soil Testing and What it Means to You Bertram Gersten and Wm. G. Colby (A-19) Lessons Learned from the 1958 Season as Applied to Golf Course Maintenance by A.M. Radko (A-21) The Outlook in Chemical Weed Control on Fine Turf by John Gallagher (A-24) New Developments in Turfgrass Disease Diagnosis and Control by Frank Howard (A-26